Features of CD4+ lymphocytes apoptosis in children with cryptosporidiosis

The aim of this study was to identify the features CD4+ lymphocytes apoptosis in children with cryptosporidiosis. Feces for detection cryptosporidium and venous blood were material study. Mononuclear leukocytes isolated from whole cultured a complete culture medium. Cells incubated 24 hours inducers receptor (TNFα) mitochondrial pathways (dexamethasone). Cryptosporidia have been found 35% acute intestinal infections children. number cytoflurimetric signs group cryptosporidiosis-positive patients did not differ that without cryptosporidiosis (p=0.421). There no intergroup differences expressing Fas on their surface (p=0.462). In cultures presence dexamethasone, decrease apoptotically altered registered only cryptosporidiosispositive (p=0.028). showed cryptosporidiosis, sensitivity cells induction pathway changes favor slowing down variant cell death.